Initiative for Multicenter Pragmatic Anesthesiology Clinical Trials’ (IMPACT)

This award was established by leaders of academic anesthesiology organizations that recognized there was a need to conduct large pragmatic trials in order to answer important questions in anesthesiology-related research.

Although there are several successful anesthesiology clinical trial networks around the world, there is no collaborative network in the United States. In an initial attempt to address this important opportunity, a consortium of academic anesthesiology organizations launched an initiative in 2018 to stimulate pragmatic research in the US.

This effort was conceptualized and endorsed by organizations, which have as a common goal the advancement of knowledge in anesthesiology and the enhancement of care in perioperative medicine, critical care, pain management, and peri- and post-partum care. These organizations included:

This year the call for letter of intents will open on Monday, October 1, 2018 and close on November 16, 2018 at 11:59 pm EST. Please click here to access our online application portal and to view submission guidelines and details.

Multicenter Pragmatic Anesthesiology Clinical Trials’ (IMPACT) Program
Sunday May 19, 2019, Montreal, Canada

Join us in hosting our second ‘Initiative for Multicenter Pragmatic Anesthesiology Clinical Trials’ (IMPACT) program in Montreal on Sunday May 19, 2019 during the IARS, AUA, SOCCA Annual meetings.

We plan to showcase promising pragmatic trials from some of tomorrow’s leaders in anesthesiology research. This important meeting will be open to those interested in anesthesiology-related clinical and translational science. The agenda for symposium will include:

  • Panel on innovative and efficient approaches to multicenter clinical trials.
  • Presentation and review of three selected clinical trial protocols. The review will include constructive feedback regarding clarity of hypotheses, merit of research methods, and feasibility. The goal of the review panel is to address issues common to many proposals to ensure an educational experience for all investigators who attend the symposium, in addition to those whose proposals are selected.

Call for Letter of Intents – for 2019 IMPACT Award

We are soliciting letters of intent for clinical research proposals from investigators who are interested in leading a pragmatic clinical trial.

This invitation is for investigators to submit letters of intent for pragmatic clinical trials in perioperative medicine. The clinical research proposals will have a high probability of receiving support from the National Institutes of Health (NIH) or another funding agency. Outcomes should be clinically relevant and important to the society.

  • Call for Letter of Intent Opens: Monday, October 1, 2018
  • Submission Deadline: Friday, November 16, 2018 at 11:59 pm EST

Please review the 2019 IMPACT Award Guidelines before developing your letters of intent.

Letters of Intent should include:

  • Descriptive title of proposed research
  • Name, address, and telephone number of the Principal Investigator(s)
  • Names of other key personnel
  • Participating institutions
  • Number and title of the funding opportunity
  • Specific Aims
Clinical Trial Categories

The clinical trials should focus on any or all of the following areas:

  • Operating Room Management
  • Pain Management
  • Peri- and Postpartum Care
  • Perioperative Critical Care
  • Postoperative Management
  • Preoperative Care/Optimization
Submission Details

You can submit you letter of intent online by clicking here. We will only take submissions submitted online through our online portal.

Past Recipients


Michael Aziz, MD
Optimized Opioid Management or Usual Treatment to Reduce Persistent Opioid Use Following Surgery (OPT-OUT).
Anesthesiology & Preoperative Medicine
Oregon Health & Science University

Randall Blank, MD, PhD
Individualized Intraoperative Protective Ventilation using an Open Lung Approach with Driving Pressure Limitation.
Associate Professor of Anesthesiology
Chief, Thoracic Anesthesia
Department of Anesthesiology
University of Virginia Health System

Frederic T. (Josh) Billings IV, MD, MSc
Intraoperative Normoxia versus Hyperoxia during Maintenance Anesthesia to Reduce Postoperative Complications.
Associate Professor of Anesthesiology and Medicine
Co-director, BH Robbins Scholars Physician-Scientist Development Program
Vanderbilt University